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Mitochondrial fusion promoter M1

CAS No. 219315-22-7

Mitochondrial fusion promoter M1( —— )

Catalog No. M23990 CAS No. 219315-22-7

Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Mitochondrial fusion promoter M1
  • Note
    Research use only, not for human use.
  • Brief Description
    Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator.
  • Description
    Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates cardiac and brain damage in rats with cardiac ischemia/reperfusion injury.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Wistar rats (250-300g) receiving cardiac ischemia/reperfusion (I/R)Dosage:2 mg/kg Administration:I.v. 15 minutes before cardiac I/R injury Result:Increased brain mitochondrial fusion.Increased blood-brain barrier (BBB) tight junction protein, and reduced macrophage in?ltration in the brain.Reduced brain mitochondrial dysfunction and apoptosis, but it did not reduce mitochondrial oxidative stress.Reduced the expression of Alzheimer’s disease (AD)-related proteins.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Mitochondria
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    219315-22-7
  • Formula Weight
    364.05
  • Molecular Formula
    C14H10Cl4N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:46 mg/mL?(126.35 mM;?Need ultrasonic)
  • SMILES
    CC(c(cc(cc1)Cl)c1O)=NNc(c(Cl)cc(Cl)c1)c1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Surinkaew P, et, al. Mitochondrial Fusion Promoter Alleviates Brain Damage in Rats with Cardiac Ischemia/Reperfusion Injury. J Alzheimers Dis. 2020;77(3):993-1003.
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